Inhibits Obesity in Mice
In mice fed a high-fat diet, 5-Amino-1MQ lowered body weight by about 5 %, reduced belly fat by roughly 35 %, and shrank fat cell size by over 30 %. It also cut cholesterol by about 30 %, all without reducing how much the mice ate.
Microbiome Reset with Diet
When paired with a low-fat diet, 5-Amino-1MQ helped obese mice regain a body composition closer to lean animals. It also shifted gut bacteria, increasing beneficial Lactobacillus and reducing harmful Erysipelatoclostridium, in ways that diet alone did not achieve.
Boosts Strength and Endurance
Older mice given 5-Amino-1MQ showed grip strength gains of about 40 %, greater than with exercise alone. Combining the compound with exercise produced around 60 % improvements, along with longer-lasting boosts in endurance, suggesting powerful combined benefits for muscle health.